QHap accelerates haplotype phasing by recasting it as a Max-Cut problem solved via GPU-accelerated simulated bifurcation, achieving 4-20x speedups with zero switch error on MHC regions and scaling to chromosome level with Pore-C data.
S., Ulahannan, N.et al.Identifying syn- ergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing.Nat
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QHap: Quantum-Inspired Haplotype Phasing
QHap accelerates haplotype phasing by recasting it as a Max-Cut problem solved via GPU-accelerated simulated bifurcation, achieving 4-20x speedups with zero switch error on MHC regions and scaling to chromosome level with Pore-C data.