A new adaptive variance estimator for relative sparsity coefficients is introduced that fully utilizes the prior asymptotic normality theorem and incorporates variable selection effects.
Continuous State-Space Models for Optimal Sepsis Treatment - a Deep Reinforcement Learning Approach
3 Pith papers cite this work. Polarity classification is still indexing.
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abstract
Sepsis is a leading cause of mortality in intensive care units (ICUs) and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and there is no universally agreed-upon treatment for sepsis. Understanding more about a patient's physiological state at a given time could hold the key to effective treatment policies. In this work, we propose a new approach to deduce optimal treatment policies for septic patients by using continuous state-space models and deep reinforcement learning. Learning treatment policies over continuous spaces is important, because we retain more of the patient's physiological information. Our model is able to learn clinically interpretable treatment policies, similar in important aspects to the treatment policies of physicians. Evaluating our algorithm on past ICU patient data, we find that our model could reduce patient mortality in the hospital by up to 3.6% over observed clinical policies, from a baseline mortality of 13.7%. The learned treatment policies could be used to aid intensive care clinicians in medical decision making and improve the likelihood of patient survival.
verdicts
UNVERDICTED 3representative citing papers
LLMs cannot solve the medical treatment problem through imitation alone because it requires evidence from experiments or observations, posing ethical challenges for training such systems.
This survey compiles deep reinforcement learning algorithms for clinical decision support, reviews case studies, and offers guidance on algorithm selection for medical applications.
citing papers explorer
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An adaptive variance estimator for relative sparsity
A new adaptive variance estimator for relative sparsity coefficients is introduced that fully utilizes the prior asymptotic normality theorem and incorporates variable selection effects.
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Treatment, evidence, imitation, and chat
LLMs cannot solve the medical treatment problem through imitation alone because it requires evidence from experiments or observations, posing ethical challenges for training such systems.
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Deep Reinforcement Learning for Clinical Decision Support: A Brief Survey
This survey compiles deep reinforcement learning algorithms for clinical decision support, reviews case studies, and offers guidance on algorithm selection for medical applications.