A cross-fitted one-step estimator that adjusts for a right-censored negative control outcome event time reduces variance by up to 27 percent in an HIV prevention trial, with multiple robustness and asymptotic efficiency.
Agnostic notes on regression adjustments to experimental data: Reexamining freed- man’s critique.Annals of Applied Statistics, 7:295–318, 2013
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Improving the efficiency of infectious disease prevention trials using negative control outcome event times
A cross-fitted one-step estimator that adjusts for a right-censored negative control outcome event time reduces variance by up to 27 percent in an HIV prevention trial, with multiple robustness and asymptotic efficiency.