Simulation study using persistent homology on 2450 nuclei shows DSB topology encodes particle identity, SOBP position, and oxygen tension with balanced accuracies from 1.000 down to 0.189 depending on LET.
Robert and Partridge, M
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Topological structure of radiation-induced DNA damage encodes coupled LET-oxygen signatures
Simulation study using persistent homology on 2450 nuclei shows DSB topology encodes particle identity, SOBP position, and oxygen tension with balanced accuracies from 1.000 down to 0.189 depending on LET.