For CT radiomics of lung nodules, harmonizing benign and malignant nodules separately or with a biological covariate beats collective harmonization at preserving features and predicting malignancy.
https://www.cancer.org/content/dam/cancer.org/research/cancer-facts-and-statistics/global-cancer-fact s-and-figures/global-cancer facts-and-figures-2024.pdf
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Training Set Augmentation and Biology-Aware Harmonization Improve Radiomic Models for Lung Cancer Prediction in Indeterminate Nodules
For CT radiomics of lung nodules, harmonizing benign and malignant nodules separately or with a biological covariate beats collective harmonization at preserving features and predicting malignancy.