A Bayesian NMF model with a correlated multivariate normal prior for mutational signatures is proposed, but the claimed accuracy gain is only demonstrated in favorable simulations.
Probabilistic interpretations of non-negative matrix factorization
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Bayesian Non-Negative Matrix Factorization with Correlated Mutation Type Probabilities for Mutational Signatures
A Bayesian NMF model with a correlated multivariate normal prior for mutational signatures is proposed, but the claimed accuracy gain is only demonstrated in favorable simulations.