A two-scale model coupling cell-scale multiphase-field dynamics to tissue-scale Helfrich bending reproduces known vesicle shapes and shows that neighbor-dependent bending rigidity can break symmetry and rotate the tissue.
Advances in Physics 46, 13–137 (1997)
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Towards a two-scale model for morphogenesis -- How cellular processes influence tissue deformations
A two-scale model coupling cell-scale multiphase-field dynamics to tissue-scale Helfrich bending reproduces known vesicle shapes and shows that neighbor-dependent bending rigidity can break symmetry and rotate the tissue.