In simulated sickle cell blood, stiff marginated sickle red blood cells preferentially enter low-flow branches at bifurcations, while healthy cells keep the usual high-flow preference, and this alters wall shear stress patterns.
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Red blood cell partitioning and segregation through vascular bifurcations in a model of sickle cell disease
In simulated sickle cell blood, stiff marginated sickle red blood cells preferentially enter low-flow branches at bifurcations, while healthy cells keep the usual high-flow preference, and this alters wall shear stress patterns.