A phantom-reactant sampling scheme lets particle-based simulations reproduce non-elementary bimolecular kinetics (Michaelis-Menten and Hill) without explicitly simulating fast elementary reactions.
Whole-cell simulation: a grand challenge of the 21st century
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Particle-based simulation of non-elementary bimolecular kinetics
A phantom-reactant sampling scheme lets particle-based simulations reproduce non-elementary bimolecular kinetics (Michaelis-Menten and Hill) without explicitly simulating fast elementary reactions.