Using genetic instruments and Hi-C contacts, the authors built causal gene networks and identified nine genes with differential regulation in schizophrenia plus candidate new risk genes.
We conclude that genetic variation in the context of schizophrenia works as cis-regulatory elements for genes that are not so much involved in trans-regulatory interactions
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Transcriptomic Causal Networks identified patterns of differential gene regulation in human brain from Schizophrenia cases versus controls
Using genetic instruments and Hi-C contacts, the authors built causal gene networks and identified nine genes with differential regulation in schizophrenia plus candidate new risk genes.