A new benchmarking framework shows virtual cell models overestimate performance on standard tests, drop sharply on unseen contexts and perturbations, and produce inconsistent rankings across metrics.
A mini-review on perturbation modelling across single-cell omic modalities.Computational and Structural Biotechnology Journal, 23:1886–1896
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
q-bio.CB 1years
2026 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
Benchmarking virtual cell models for in-the-wild perturbation response
A new benchmarking framework shows virtual cell models overestimate performance on standard tests, drop sharply on unseen contexts and perturbations, and produce inconsistent rankings across metrics.