The paper reports an MLP classifier on 25 CpG methylation features that distinguishes colorectal cancer from normal cfDNA with AUROC 0.89 on a hold-out set, but the validation is compromised by feature selection on the full dataset.
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In silico tool for identification of colorectal cancer from cell-free DNA biomarkers
The paper reports an MLP classifier on 25 CpG methylation features that distinguishes colorectal cancer from normal cfDNA with AUROC 0.89 on a hold-out set, but the validation is compromised by feature selection on the full dataset.