A coupled patient-device respiratory model integrating lung mechanics, gas exchange, and respiratory control is validated as fit-for-purpose for preclinical in silico trials of automated weaning under ASME V&V 40 and FDA guidelines.
A Mathemati- cal Model of the Human Respiratory Con- trol System
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Irregular curvature at focal adhesions in cancer cells preserves Piezo1 activity under LIUS while regular curvature in healthy cells reduces it via cholesterol effects, providing a proposed basis for selective apoptosis.
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Validation of a Computational Respiratory System Model for Mechanical Ventilation
A coupled patient-device respiratory model integrating lung mechanics, gas exchange, and respiratory control is validated as fit-for-purpose for preclinical in silico trials of automated weaning under ASME V&V 40 and FDA guidelines.
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Irregular curvature at focal adhesions modulates Piezo1 activity and low frequency ultrasound induced apoptosis in cancer cells
Irregular curvature at focal adhesions in cancer cells preserves Piezo1 activity under LIUS while regular curvature in healthy cells reduces it via cholesterol effects, providing a proposed basis for selective apoptosis.