DPLM-Evo adds explicit edit operations and a latent alignment space to discrete diffusion protein models, achieving SOTA single-sequence mutation effect prediction on ProteinGym while supporting variable-length generation.
Prottrans: Toward understanding the language of life through self-supervised learning.IEEE transactions on pattern analysis and machine intelligence, 44(10): 7112–7127, 2021
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Towards A Generative Protein Evolution Machine with DPLM-Evo
DPLM-Evo adds explicit edit operations and a latent alignment space to discrete diffusion protein models, achieving SOTA single-sequence mutation effect prediction on ProteinGym while supporting variable-length generation.