RIDER improves RNA 3D structural similarity by over 100% using RL-guided diffusion and discovers non-native sequence designs.
Ribozymes, riboswitches and beyond: regulation of gene expression without proteins.Nature Reviews Genetics, 8(10):776–790, 2007
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RIDER: 3D RNA Inverse Design with Reinforcement Learning-Guided Diffusion
RIDER improves RNA 3D structural similarity by over 100% using RL-guided diffusion and discovers non-native sequence designs.