EvoIF integrates within-family and cross-family evolutionary signals into a compact model to achieve competitive or state-of-the-art zero-shot fitness prediction on ProteinGym using only 0.15% of typical training data.
Amix- 1: A pathway to test-time scalable protein foundation model.arXiv preprint arXiv: 2507.08920, 2025
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Evolutionary Profiles for Protein Fitness Prediction
EvoIF integrates within-family and cross-family evolutionary signals into a compact model to achieve competitive or state-of-the-art zero-shot fitness prediction on ProteinGym using only 0.15% of typical training data.