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SA-MDKIF: A Scalable and Adaptable Medical Domain Knowledge Injection Framework for Large Language Models

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abstract

Recent advances in large language models (LLMs) have demonstrated exceptional performance in various natural language processing (NLP) tasks. However, their effective application in the medical domain is hampered by a lack of medical domain knowledge. In this study, we present SA-MDKIF, a scalable and adaptable framework that aims to inject medical knowledge into general-purpose LLMs through instruction tuning, thereby enabling adaptability for various downstream tasks. SA-MDKIF consists of two stages: skill training and skill adaptation. In the first stage, we define 12 basic medical skills and use AdaLoRA to train these skills based on uniformly formatted instructional datasets that we have constructed. In the next stage, we train the skill router using task-specific downstream data and use this router to integrate the acquired skills with LLMs during inference. Experimental results on 9 different medical tasks show that SA-MDKIF improves performance by 10-20% compared to the original LLMs. Notably, this improvement is particularly pronounced for unseen medical tasks, showing an improvement of up to 30%.

fields

cs.CL 1

years

2025 1

verdicts

CONDITIONAL 1

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Survey of Specialized Large Language Model

cs.CL · 2025-08-27 · conditional · novelty 2.0

A survey of 24 specialized LLMs (2022-2025) claims a shift from domain fine-tuning to native architectures, but the synthesis is undermined by citation errors and selection bias.

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  • Survey of Specialized Large Language Model cs.CL · 2025-08-27 · conditional · none · ref 40 · internal anchor

    A survey of 24 specialized LLMs (2022-2025) claims a shift from domain fine-tuning to native architectures, but the synthesis is undermined by citation errors and selection bias.