A biokinetic model calibrated on 56 clinical datasets predicts patient-specific radiation-induced lymphopenia and quantifies a 30 percent reduction in lymphocyte depletion with particle therapy versus photon therapy.
Relationships between lymphocyte counts and treatment-related toxicities and clinical responses in patients with solid tumors treated with PD-1 checkpoint inhibitors
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Model-aided quantification of patient-specific benefit in mitigating radiation induced lymphopenia by particle therapy of cancer
A biokinetic model calibrated on 56 clinical datasets predicts patient-specific radiation-induced lymphopenia and quantifies a 30 percent reduction in lymphocyte depletion with particle therapy versus photon therapy.