This survey claims to be the first systematic review of LLMs for organic synthesis, but its central 'evaluation' is never actually performed.
Prompt Sentiment: The Catalyst for LLM Change
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abstract
The rise of large language models (LLMs) has revolutionized natural language processing (NLP), yet the influence of prompt sentiment, a latent affective characteristic of input text, remains underexplored. This study systematically examines how sentiment variations in prompts affect LLM-generated outputs in terms of coherence, factuality, and bias. Leveraging both lexicon-based and transformer-based sentiment analysis methods, we categorize prompts and evaluate responses from five leading LLMs: Claude, DeepSeek, GPT-4, Gemini, and LLaMA. Our analysis spans six AI-driven applications, including content generation, conversational AI, legal and financial analysis, healthcare AI, creative writing, and technical documentation. By transforming prompts, we assess their impact on output quality. Our findings reveal that prompt sentiment significantly influences model responses, with negative prompts often reducing factual accuracy and amplifying bias, while positive prompts tend to increase verbosity and sentiment propagation. These results highlight the importance of sentiment-aware prompt engineering for ensuring fair and reliable AI-generated content.
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Large Language Models Transform Organic Synthesis From Reaction Prediction to Automation
This survey claims to be the first systematic review of LLMs for organic synthesis, but its central 'evaluation' is never actually performed.