For leaky vaccines, common empirical VE estimates must be adjusted to match model parameters, resulting in predictions of fewer infections and lower herd immunity thresholds than naive parameterization.
Optimal vaccination strategies for imperfect vaccines and variable host susceptibility.Jour- nal of Theoretical Biology, 594:111899, nov 2024
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Incorporating vaccine effects into epidemiological models: common pitfalls and solutions
For leaky vaccines, common empirical VE estimates must be adjusted to match model parameters, resulting in predictions of fewer infections and lower herd immunity thresholds than naive parameterization.