Funnels in Energy Landscapes
classification
🧬 q-bio.BM
keywords
foldingenergyfunnelminimanotionpointssaddlebiopolymer
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Local minima and the saddle points separating them in the energy landscape are known to dominate the dynamics of biopolymer folding. Here we introduce a notion of a "folding funnel" that is concisely defined in terms of energy minima and saddle points, while at the same time conforming to a notion of a "folding funnel" as it is discussed in the protein folding literature.
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