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arxiv: 0908.2022 · v1 · pith:IHBJ6HAAnew · submitted 2009-08-14 · 🧬 q-bio.PE · q-bio.QM

The intermediate evolution phase in case of truncated selection

classification 🧬 q-bio.PE q-bio.QM
keywords casefitnessintermediatelandscapephasequasispeciestruncatedapplicable
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Using methods of statistical physics, we present rigorous theoretical calculations of Eigen's quasispecies theory with the truncated fitness landscape which dramatically limits the available sequence space of a reproducing quasispecies. Depending on the mutation rates, we observe three phases, a selective one, an intermediate one with some residual order and a completely randomized phase. Our results are applicable for the general case of fitness landscape.

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