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arxiv: 1007.3130 · v1 · submitted 2010-07-19 · 🧮 math.PR · math.NA· q-bio.QM

Bounding the Equilibrium Distribution of Markov Population Models

classification 🧮 math.PR math.NAq-bio.QM
keywords statesystemsbiologicalboundsdistributionequilibriummarkovsteady
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Arguing about the equilibrium distribution of continuous-time Markov chains can be vital for showing properties about the underlying systems. For example in biological systems, bistability of a chemical reaction network can hint at its function as a biological switch. Unfortunately, the state space of these systems is infinite in most cases, preventing the use of traditional steady state solution techniques. In this paper we develop a new approach to tackle this problem by first retrieving geometric bounds enclosing a major part of the steady state probability mass, followed by a more detailed analysis revealing state-wise bounds.

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