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arxiv: 1304.3691 · v1 · pith:6ZLDRZDZnew · submitted 2013-04-12 · 🧬 q-bio.PE

Identifiability of a Coalescent-based Population Tree Model

classification 🧬 q-bio.PE
keywords modeltreebeenidentifiabilitypopulationcoalescent-basedmodelsaccurately
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Identifiability of evolutionary tree models has been a recent topic of discussion and some models have been shown to be non-identifiable. A coalescent-based rooted population tree model, originally proposed by Nielsen et al. 1998 [2], has been used by many authors in the last few years and is a simple tool to accurately model the changes in allele frequencies in the tree. However, the identifiability of this model has never been proven. Here we prove this model to be identifiable by showing that the model parameters can be expressed as functions of the probability distributions of subsamples. This a step toward proving the consistency of the maximum likelihood estimator of the population tree based on this model.

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