Isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard
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🧬 q-bio.QM
q-bio.GN
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isoformlikelihoodmaximumreconstructionnp-hardreadsrna-seqshort
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Maximum likelihood is a popular technique for isoform reconstruction. Here, we show that isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard.
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