Large scale statistical analysis of GEO datasets
classification
📊 stat.ME
q-bio.GN
keywords
datasetsanalysisdifferentexpressiongenelargescalestatistical
read the original abstract
The problem addressed here is that of simultaneous treatment of several gene expression datasets, possibly collected under different experimental conditions and/or platforms. Using robust statistics, a large scale statistical analysis has been conducted over $20$ datasets downloaded from the Gene Expression Omnibus repository. The differences between datasets are compared to the variability inside a given dataset. Evidence that meaningful biological information can be extracted by merging different sources is provided.
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