Separation with restricted families of sets

Given a finite $n$-element set $X$, a family of subsets ${\mathcal F}\subset 2^X$ is said to separate $X$ if any two elements of $X$ are separated by at least one member of $\mathcal F$. It is shown that if $|\mathcal F|>2^{n-1}$, then one can select $\lceil\log n\rceil+1$ members of $\mathcal F$ that separate $X$. If $|\mathcal F|\ge \alpha 2^n$ for some $0<\alpha<1/2$, then $\log n+O(\log\frac1{\alpha}\log\log\frac1{\alpha})$ members of $\mathcal F$ are always sufficient to separate all pairs of elements of $X$ that are separated by some member of $\mathcal F$. This result is generalized to simultaneous separation in several sets. Analogous questions on separation by families of bounded Vapnik-Chervonenkis dimension and separation of point sets in ${\mathbb{R}}^d$ by convex sets are also considered.