Rational homology balls in 2-handlebodies

We prove that there are rational homology balls $B_p$ smoothly embedded in the $2$-handlebodies associated to certain knots. Furthermore we show that, if we rationally blow up the $2$-handlebody along the embedded rational homology ball $B_p$, then the resulting $4$-manifold cannot be obtained just by a sequence of ordinary blow ups from the $2$-handlebody under a certain mild condition.