Bridging trees for posterior inference on Ancestral Recombination Graphs
classification
📊 stat.CO
q-bio.PE
keywords
bridgingalgorithmancestralappliedarboresbridgecarlochain
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We present a new Markov chain Monte Carlo algorithm, implemented in software Arbores, for inferring the history of a sample of DNA sequences. Our principal innovation is a bridging procedure, previously applied only for simple stochastic processes, in which the local computations within a bridge can proceed independently of the rest of the DNA sequence, facilitating large-scale parallelisation.
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