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arxiv: 1812.01345 · v1 · pith:VBZD36RLnew · submitted 2018-12-04 · 📊 stat.CO · q-bio.PE

Bridging trees for posterior inference on Ancestral Recombination Graphs

classification 📊 stat.CO q-bio.PE
keywords bridgingalgorithmancestralappliedarboresbridgecarlochain
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We present a new Markov chain Monte Carlo algorithm, implemented in software Arbores, for inferring the history of a sample of DNA sequences. Our principal innovation is a bridging procedure, previously applied only for simple stochastic processes, in which the local computations within a bridge can proceed independently of the rest of the DNA sequence, facilitating large-scale parallelisation.

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