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arxiv: 1904.11372 · v1 · pith:REC3OMU3 · submitted 2019-04-16 · q-bio.CB · nlin.AO· q-bio.PE

A Multi-agent approach for textit{in silico} simulations of micro-biological systems

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classification q-bio.CB nlin.AOq-bio.PE
keywords systemstextitmicro-biologicalmulti-agentnamelysimulationssocialaddition
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Using a Multi-agent systems paradigm, the present project develops, validates and exploits a computational $\textit{testbed}$ that simulates micro-biological complex systems, namely the aggregation patterns of the social amoeba $\textit{Dyctiostelium discoideum}$. We propose a new design and implementation for managing discrete simulations with autonomous agents on a microscopic scale, thus focusing on their social behavior and mutual interactions. Then, the dependence on the main physical variables is tested, namely density and number of amoebas; in addition, we analyze the robustness of the dynamics against various noise sources. Along with these results, we suggest a methodology for further studies that make use of our validated model.

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