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Bayesian Spatial Homogeneity Pursuit for Survival Data with an Application to the SEER Respiratory Cancer Data

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arxiv 2003.03006 v2 pith:I7J5WQML submitted 2020-03-06 stat.AP stat.ME

classification stat.APstat.ME
keywords datahomogeneitybaselinecoefficientsspatialbayesiancancerhazard
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In this work, we propose a new Bayesian spatial homogeneity pursuit method for survival data under the proportional hazards model to detect spatially clustered patterns in baseline hazard and regression coefficients. Specially, regression coefficients and baseline hazard are assumed to have spatial homogeneity pattern over space. To capture such homogeneity, we develop a geographically weighted Chinese restaurant process prior to simultaneously estimate coefficients and baseline hazards and their uncertainty measures. An efficient Markov chain Monte Carlo (MCMC) algorithm is designed for our proposed methods. Performance is evaluated using simulated data, and further applied to a real data analysis of respiratory cancer in the state of Louisiana.

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