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arxiv: adap-org/9708004 · v1 · submitted 1997-08-06 · adap-org · nlin.AO· q-bio

Symmetry Breaking and Adaptation: Evidence from a Toy Model of a Virus

classification adap-org nlin.AOq-bio
keywords virusbreakingclaimepitopeimmunemodelsymmetryability
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We argue that the phenomenon of symmetry breaking in genetics can enhance the adaptability of a species to changes in the environment. In the case of a virus, the claim is that the codon bias in the neutralization epitope improves the virus' ability to generate mutants that evade the induced immune response. We support our claim with a simple ``toy model'' of a viral epitope evolving in competition with the immune system. The effective selective advantage of a higher mutability leads to a dominance of codons that favour non-synonymous mutations. The results in this paper suggest the possibility of emergence of an algorithmic language in more complicated systems.

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