Combinatorics and invariant differential operators on multiplicity free spaces

We study the generalization of shifted Jack polynomials to arbitrary multiplicity free spaces. In a previous paper (math.RT/0006004) we showed that these polynomials are eigenfunctions for commuting difference operators. Our central result now is the "transposition formula", a generalization of Okounkov's binomial theorem (q-alg/9608021) for shifted Jack polynomials. From this formula, we derive an interpolation formula, an evaluation formula, a scalar product, a binomial theorem, and properties of the algebra generated by the multiplication and difference operators.