Fibred knots and twisted Alexander invariants

We introduce a new algebraic topological technique to detect non-fibred knots in the three sphere using the twisted Alexander invariants. As an application, we show that for any Seifert matrix of a knot with a nontrivial Alexander polynomial, there exist infinitely many non-fibered knots with the given Seifert matrix. We illustrate examples of knots that have trivial Alexander polynomials but do not have twisted Alexander invariants of fibred knots.