Optimal Path to Epigenetic Switching
classification
🧬 q-bio.MN
q-bio.CB
keywords
analyzebiochemicalcalculatecircuitcomparedeviationepigeneticequation
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We use large deviation methods to calculate rates of noise-induced transitions between states in multistable genetic networks. We analyze a synthetic biochemical circuit, the toggle switch, and compare the results to those obtained from a numerical solution of the master equation.
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