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arxiv: 0804.1202 · v1 · submitted 2008-04-08 · 🧬 q-bio.BM · q-bio.QM

A Preliminary Work on Evolutionary Identification of Protein Variants and New Proteins on Grids

classification 🧬 q-bio.BM q-bio.QM
keywords proteinproteinsapproachidentificationvariantsevolutionaryspectrabeen
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Protein identification is one of the major task of Proteomics researchers. Protein identification could be resumed by searching the best match between an experimental mass spectrum and proteins from a database. Nevertheless this approach can not be used to identify new proteins or protein variants. In this paper an evolutionary approach is proposed to discover new proteins or protein variants thanks a "de novo sequencing" method. This approach has been experimented on a specific grid called Grid5000 with simulated spectra and also real spectra.

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