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Arc-Completion of 2-Colored Best Match Graphs to Binary-Explainable Best Match Graphs

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arxiv 2103.06665 v1 pith:OMAKEFJU submitted 2021-03-11 cs.DS cs.DMmath.COq-bio.PE

classification cs.DScs.DMmath.COq-bio.PE
keywords bestbmgsgraphsleastmatchresolvedtreetrees
verification ladder T0 review T1 audit T2 compute T3 formal
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Best match graphs (BMGs) are vertex-colored digraphs that naturally arise in mathematical phylogenetics to formalize the notion of evolutionary closest genes w.r.t. an a priori unknown phylogenetic tree. BMGs are explained by unique least resolved trees. We prove that the property of a rooted, leaf-colored tree to be least resolved for some BMG is preserved by the contraction of inner edges. For the special case of two-colored BMGs, this leads to a characterization of the least resolved trees (LRTs) of binary-explainable trees and a simple, polynomial-time algorithm for the minimum cardinality completion of the arc set of a BMG to reach a BMG that can be explained by a binary tree.

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