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Complexity and Enumeration in Models of Genome Rearrangement

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arxiv 2305.01851 v4 pith:6H7Q55LA submitted 2023-05-03 q-bio.GN cs.CCmath.CO

classification q-bio.GNcs.CCmath.CO
keywords rearrangementtextsfbiolcomplexityenumerationgenomemodelmodels
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abstract

In this paper, we examine the computational complexity of enumeration in certain genome rearrangement models. We first show that the Pairwise Rearrangement problem in the Single Cut-and-Join model (Bergeron, Medvedev, & Stoye, J. Comput. Biol. 2010) is $\#\textsf{P}$-complete under polynomial-time Turing reductions. Next, we show that in the Single Cut or Join model (Feijao & Meidanis, IEEE ACM Trans. Comp. Biol. Bioinf. 2011), the problem of enumerating all medians ($\#$Median) is logspace-computable ($\textsf{FL}$), improving upon the previous polynomial-time ($\textsf{FP}$) bound of Mikl\'os & Smith (RECOMB 2015).

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