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Magnetic Milli-spinner for Robotic Endovascular Surgery
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Vascular diseases such as thrombosis, atherosclerosis, and aneurysm, which can lead to blockage of blood flow or blood vessel rupture, are common and life-threatening. Conventional minimally invasive treatments utilize catheters, or long tubes, to guide small devices or therapeutic agents to targeted regions for intervention. Unfortunately, catheters suffer from difficult and unreliable navigation in narrow, winding vessels such as those found in the brain. Magnetically actuated untethered robots, which have been extensively explored as an alternative, are promising for navigation in complex vasculatures and vascular disease treatments. Most current robots, however, cannot swim against high flows or are inadequate in treating certain conditions. Here, we introduce a multifunctional and magnetically actuated milli-spinner robot for rapid navigation and performance of various treatments in complicated vasculatures. The milli-spinner, with a unique hollow structure including helical fins and slits for propulsion, generates a distinct flow field upon spinning. The milli-spinner is the fastest-ever untethered magnetic robot for movement in tubular environments, easily achieving speeds of 23 cm/s, demonstrating promise as an untethered medical device for effective navigation in blood vessels and robotic treatment of numerous vascular diseases.
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Cited by 1 Pith paper
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Clot Treatment via Compression- and Shear-Induced Densification of Fibrin Network Microstructure: A Combined in Vitro and In Silico Investigation
Compression and shear jointly densify fibrin networks, with shear as the dominant driver of red blood cell release; a DPD model calibrated to one experiment reproduces the main trends.
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