Typed states for the displayed outbound observations.
Source: paper_references, paper_reference_links, observed 2026-08-15T18:00:35.318441Z
Paper Citation Record · LEDGER
As of 19 August 2026, this Paper Citation Record lists 61 of 61 outbound references and 1 inbound Pith citation observation for arXiv:2507.19375.
A citation records a reference. It does not transfer a finding from one paper to another.
Typed states for the displayed outbound observations.
Source: paper_references, paper_reference_links, observed 2026-08-15T18:00:35.318441Z
One-hop event checks from named stored sources.
Source: scholarly_work_events, retraction_status_cache, observed 2026-08-19T06:32:44.657259+00:00
Pith citing papers itemized under the disclosed page cap.
Source: paper_references, paper_reference_links, observed 2026-07-12T02:29:52.764344Z
A source-named dated measurement, never combined with another source.
Source: pith, observed 2026-08-05T02:28:24.338817Z
61 of 61 outbound references displayed
External citation measurements
1
pith, observed 2026-08-05T02:28:24.338817Z
Observation 10fc5b39-a429-43a4-a372-348049097fb1 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Therapeutic proteins.Therapeutic Proteins: Methods and Protocols, pages 1–26, 2012
Reference 1
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 40c2b638-0a3e-4047-a4eb-db3c9db8151b · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials
Reference 2
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation d882d730-e447-416b-b9b5-d8db9c02ab10 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Engineering protein-based therapeutics through structural and chemical design.Nature communications, 14(1):2411, 2023
Reference 3
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 695a01ea-6d8e-48cb-85ae-16cf10af45f9 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design The exploration of macrocycles for drug discovery—an underexploited structural class.Nature Reviews Drug Discovery, 7(7):608–624, 2008
Reference 4
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 84d16d32-783c-4811-9a43-32821daf0ec0 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Macrocyclic peptides as drug candidates: Recent progress and remaining challenges.Journal of the American Chemical Society, 141(10):4167–4181, 2019
Reference 5
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation d5ebdabf-b921-49a6-99fa-48ede440eec5 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Massively parallel de novo protein design for targeted therapeutics.Nature, 550(7674):74–79, 2017
Reference 6
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation a2971e5d-3a96-49bc-a078-81b1a0081a1a · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
Reference 7
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation e29b8a6f-e2f7-4290-9df2-e8b87c2f2c5e · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design An enumerative algorithm for de novo design of proteins with diverse pocket structures.Proceedings of the National Academy of Sciences, 117(36):22135–22145, 2020
Reference 8
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation c50e2707-5c45-42b8-a938-ac4eed7d851e · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Design of protein-binding proteins from the target structure alone.Nature, 605(7910):551–560, 2022
Reference 9
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation eaefa601-9f6b-41b9-9ea8-b1b89fda982f · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Highly accurate protein structure prediction with AlphaFold.nature, 596(7873):583–589, 2021
Reference 10
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation e9506a28-bf38-4a14-b558-6588806329b3 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Diffusion probabilistic modeling of protein backbones in 3D for the motif-scaffolding problem
Reference 11
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation 909b57e2-e1e5-4815-9459-b38ea1222b41 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Protein Structure and Sequence Generation with Equivariant Denoising Diffusion Probabilistic Models
Reference 12
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation 068341a1-f677-42bb-ab87-10369bdcb29e · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Scaffolding protein functional sites using deep learning
Reference 13
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 59858943-65ee-4d03-880a-b010ec3de8a8 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Illuminating protein space with a programmable generative model.Nature, 623(7989):1070–1078, 2023
Reference 14
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 394682e2-5823-489c-872d-80a4b406eafe · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Generative Flows on Discrete State-Spaces: Enabling Multimodal Flows with Applications to Protein Co-Design
Reference 15
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation 690bd077-a71c-4fa8-8764-ded030fd02ee · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Simulating 500 million years of evolution with a language model.Science, page eads0018, 2025
Reference 16
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation bd5858a2-18fc-4125-a2e0-54b211e8a816 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design An all-atomproteingenerativemodel
Reference 17
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 10561a1f-7b8d-4097-a7f9-64fd852f3fd0 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design P(all-atom) is unlocking new path for protein design.bioRxiv, pages 2024–08, 2024
Reference 18
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 0f6e14b5-1918-4eed-a389-a3ba0832b415 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design All-atom protein generation with latent diffusion
Reference 19
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation b977302a-0a0b-48c7-8cac-fbb024b16c0c · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design De novo protein design by deep network hallucination.Nature, 600(7889):547–552, 2021
Reference 20
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation 4b603b4a-ebff-4f41-b8ed-481555a79e7f · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design BindCraft: one-shot design of functional protein binders.bioRxiv, pages 2024–09, 2024
Reference 21
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation b5e03b04-e961-44fa-8eb1-686abd4bfd30 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design bioRxiv,pages2025–04,2025
Reference 22
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation bc19e9ea-7604-4ab0-94ea-d028212bc26a · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design De novo design of protein structure and function with RFdiffusion.Nature, 620(7976):1089–1100, 2023
Reference 23
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 17f60c2c-0d06-49d2-a8ba-030fcb556cd8 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design De novo design of high-affinity protein binders with AlphaProteo
Reference 24
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation 7da7daf1-ab9b-4eb0-89ee-5ea6d011c6ef · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Zero-shot antibody design in a 24-well plate.bioRxiv, 2025
Reference 25
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 0f80a2f9-3f1f-49e6-8db0-09de1cf4577f · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Accurate de novo design of high-affinity protein-binding macrocycles using deep learning.Nature Chemical Biology, pages 1–9, 2025
Reference 26
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 5645b7a0-a5b8-4a14-8de8-8a3c35c7f84a · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Robust deep learning–based protein sequence design using ProteinMPNN.Science, 378(6615):49–56, 2022
Reference 27
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation bf1294ee-03a1-4368-b30b-85b25fb1a89d · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Improving de novo protein binder design with deep learning
Reference 28
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation ea0a6d71-fc3d-41fc-a457-0f372b697a13 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design The protein data bank.Nucleic acids research, 28(1):235–242, 2000
Reference 29
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation dd8874a6-f7f7-40fe-ad9c-11f7798600e6 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design AlphaFold protein structure database Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design 18 in2024:Providingstructurecoverageforover214millionproteinsequences
Reference 30
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 416c6fd5-5fad-47c5-b0c6-3b7617aab337 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Rational approaches to improving selectivity in drug design
Reference 31
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation 8b6d7a4c-f680-474f-aa98-4865af83cd17 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells.Cell, 157(7):1644–1656, 2014
Reference 32
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation bb958783-0065-4945-9fc7-ed02a8deb0f7 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Targeting the MDM2-p53 interaction for cancer therapy.Clinical Cancer Research, 14(17):5318–5324, 2008
Reference 33
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 822e6a07-ee93-4b23-bc69-f7374e21320d · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Targeting MCL-1 protein to treat cancer: opportunities and challenges.Frontiers in oncology, 13:1226289, 2023
Reference 34
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 2bd1ebbc-7a60-468f-84ab-ae0df2564b52 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design De novo design of protein interactions with learned surface fingerprints.Nature, 617(7959):176–184, 2023
Reference 35
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation f14b7457-30b0-447d-8c73-493d1534e11d · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Preclinicalproofofprinciplefororally delivered Th17 antagonist miniproteins.Cell, 187(16):4305–4317, 2024
Reference 36
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation bb30eba5-a60a-4898-a114-1c936f8c6be2 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Antagonism of nerve growth factor-TrkA signaling and the relief of pain.Anesthesiology, 115(1):189, 2011
Reference 37
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation c30222bf-4506-4dd9-920b-8d01f1cfe8fe · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Cyclic peptide structure prediction and design using AlphaFold2.Nature Communications, 16(1):1–15, 2025
Reference 38
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation cc9fdf78-70ea-42a6-9c20-45c9e5e6e184 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Rational design of a potent macrocyclic peptide inhibitor targeting the PD-1/PD-L1 protein–protein interaction.RSC advances, 11(38): 23270–23279, 2021
Reference 39
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 53e172d6-8cbc-46d3-8e32-7945beee9467 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Discovery of cyclic peptide inhibitors targeting pd-l1 for cancer immunotherapy.Journal of medicinal chemistry, 65(18):12002–12013, 2022
Reference 40
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 92e15b74-799c-4964-b332-adb931497bb9 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets.Nature biotechnology, 35(11):1026–1028, 2017
Reference 41
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 315f4691-1d1b-4116-98b2-75f86f17296c · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Fast and accurate protein structure search with foldseek
Reference 42
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation add97229-9037-4d7a-a936-0d9ee1c29834 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Language models generalize beyond natural proteins
Reference 43
Source-reported events for the cited work
Unavailable: canonical work link unavailable.
Observation 1e56a695-f615-4691-9ec1-0b884e77a114 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Mammaliancelldisplayforantibodyengineering
Reference 44
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation cf05f4e2-0ba0-4c97-9e08-10eb596dfd19 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Beyond affinity: Selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries
Reference 45
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 38176c06-8f60-4625-96c5-7aeb25e78df0 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Macromolecular crystallographic information file (mmCIF)
Reference 46
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 6c7aaf40-371f-47bd-98ba-e5c2bbb68c7d · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design lDDT:alocalsuperposition-free score for comparing protein structures and models using distance difference tests.Bioinformatics, 29(21): 2722–2728, 2013
Reference 47
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation da4d7bf3-8519-4f4f-8742-7b3c353c651a · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Accurate structure prediction of biomolecular interactions with AlphaFold 3.Nature, pages 1–3, 2024
Reference 48
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 605f1790-1776-4a95-b611-5a9ebfbb25a3 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Chai-1: Decoding the molecular interactions of life.BioRxiv, 2024
Reference 49
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 54b236bb-cf1e-4bba-a2ad-3b22e40ef98a · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Boltz-2: Towards accurate and efficient binding Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design 19 affinity prediction
Reference 50
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 70d1083c-873c-4b6c-a19e-4605a399cb7f · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design How significant is a protein structure similarity with TM-score= 0.5? Bioinformatics, 26(7):889–895, 2010
Reference 51
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 6dd388fe-3998-4578-9b50-fb4939314c2f · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Uniref clusters: A comprehensive and scalable alternative for improving sequence similarity searches
Reference 52
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation f94afa0a-8d9e-4cd7-ad25-e401b2631e71 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Biopython: freely available python tools for computational molecular biology and bioinformatics.Bioinformatics, 25(11):1422–1423, 2009
Reference 53
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 9620e3ba-bb18-4db9-a7cc-0772f11c23c1 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features.Biopolymers: Original Research on Biomolecules , 22(12): 2577–2637, 1983
Reference 54
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation da7e8b2b-3efc-4e3d-a5e6-a342cc43e965 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Codon optimization tool
Reference 55
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation edd08171-c441-4319-aa5a-968cd0b2344b · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design The target can consist of multiple protein chains or crops of protein chains
Reference 56
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 48d88070-5af5-4a87-bae8-904d803095e1 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design At least one hotspot needs to be provided
Reference 57
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation a53b93d0-fc75-4d07-bbc9-2c49a1912edd · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Unresolved cited work
Reference 58
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 58c63254-ce96-4f45-bcd3-0c0546d06393 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Unresolved cited work
Reference 59
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 5f3cd7e5-2b8f-4222-9bee-e78d17c71304 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design hingeeffect
Reference 60
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 7390538c-2f14-4b6e-a887-f7a1e3d87aa9 · outbound
Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design Gen- Script
Reference 61
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.
Observation 93959b85-0e7a-4f97-8735-2c169b12bc38 · inbound
Design-CP: Context Parallelism for Design of Protein Nanoparticles Latent-X: An Atom-level Frontier Model for De Novo Protein Binder Design
Reference 109
Source-reported events for the cited work
No event found in the named queried sources as of 2026-08-19T06:32:44.657259+00:00.