pith. sign in

arxiv: 2604.06534 · v1 · submitted 2026-04-08 · 📡 eess.SP · eess.IV

FOSSA: First-Order Optimality-Based Sensor Selection for PINN Inverse Problems, with Application to Electrocardiographic Imaging

Pith reviewed 2026-05-10 18:40 UTC · model grok-4.3

classification 📡 eess.SP eess.IV
keywords physics-informed neural networkssensor selectioninverse problemsfirst-order optimalityelectrocardiographic imagingPINN
0
0 comments X

The pith

Sensor importance for PINN inverse problems is revealed by first-order optimality after one training run.

A machine-rendered reading of the paper's core claim, the machinery that carries it, and where it could break.

The paper proposes FOSSA to assign importance scores to candidate sensor locations for physics-informed neural network inverse problems. It does so by evaluating the first-order optimality condition once the network has converged, avoiding the need for multiple training iterations. This global assessment shows which sensors contribute to better reconstructions and which do not. Validation on electrocardiographic imaging demonstrates that including low-importance sensors can actually reduce accuracy. A refinement scheme is added to handle cases where the inverse solver is unstable.

Core claim

FOSSA evaluates the first-order optimality condition of the converged PINN to produce importance scores for all candidate sensors in a post-training step. This enables identification of sensors that positively or negatively affect the solution quality. In the electrocardiography application, the scores indicate that some sensors degrade performance when incorporated into the model.

What carries the argument

The first-order optimality condition at convergence of the PINN training, used to compute per-sensor importance scores from the data loss term.

If this is right

  • A single converged PINN model allows ranking of every possible sensor location.
  • Sensors identified as low-importance can be omitted to avoid degrading reconstruction accuracy.
  • The method avoids the computational expense of iterative sensor addition and retraining.
  • Global sensor characterization supports better deployment decisions in physics-based inverse modeling.

Where Pith is reading between the lines

These are editorial extensions of the paper, not claims the author makes directly.

  • If sensors interact strongly, the first-order scores may underestimate combined effects and require validation through targeted experiments.
  • The refinement scheme for instability could be generalized to other optimization challenges in PINNs.
  • This post-hoc analysis opens the possibility of designing sensor networks optimized for the specific physics of the problem rather than uniform placement.

Load-bearing premise

That evaluating the first-order optimality condition at a single converged solution gives a reliable measure of each sensor's marginal contribution without considering higher-order effects or sensor interactions.

What would settle it

Training the PINN with and without the lowest-ranked sensors from FOSSA and observing whether the reconstruction error in the electrocardiographic imaging problem decreases when low-importance sensors are excluded.

Figures

Figures reproduced from arXiv: 2604.06534 by Jianxin Xie.

Figure 1
Figure 1. Figure 1: Illustration of the proposed FOSSA-integrated physics-constrained inverse ECG framework. [PITH_FULL_IMAGE:figures/full_fig_p008_1.png] view at source ↗
Figure 2
Figure 2. Figure 2: Reproducibility of FOSSA-derived importance maps under different noise levels and training conditions. Each subfigure corresponds to a noise setting: [PITH_FULL_IMAGE:figures/full_fig_p008_2.png] view at source ↗
Figure 3
Figure 3. Figure 3: Reconstruction performance under different FOSSA-ranked observation sets and noise levels. (a) [PITH_FULL_IMAGE:figures/full_fig_p009_3.png] view at source ↗
Figure 4
Figure 4. Figure 4: Qualitative comparison of heart-surface potential reconstruction at a [PITH_FULL_IMAGE:figures/full_fig_p009_4.png] view at source ↗
Figure 5
Figure 5. Figure 5: Comparison of sensor selection strategies for inverse ECG reconstruction under varying sensing budgets ( [PITH_FULL_IMAGE:figures/full_fig_p011_5.png] view at source ↗
read the original abstract

Physics-informed neural networks (PINNs) have emerged as a powerful framework for modeling physical systems and solving inverse problems. In such settings, sensors are deployed to capture observable system responses; however, the quality of reconstruction critically depends on how these sensors are selected. Existing sensor selection strategies for PINNs are closely related to active learning and experimental design, typically relying on iterative refinement schemes that sequentially add sensors and retrain the model. While effective under limited data regimes, these approaches incur substantial computational cost due to repeated retraining and primarily focus on selecting subsets of sensors, without providing a global characterization of sensor importance. In this work, we propose FOSSA, a first-order optimality-based sensor selection algorithm for inverse PINNs. Unlike existing methods, FOSSA evaluates sensor importance in a post-training manner, requiring only a single trained PINN. FOSSA assigns importance scores to all candidate sensing locations based on the first-order optimality condition at convergence. To improve robustness, a refinement scheme is further proposed to handle instability in the inverse solver. FOSSA facilitates a global assessment of the contribution of each sensor to reconstruction. We validate the proposed approach on the inverse electrocardiography (ECG) modeling and show that not all sensors contribute positively to predictive performance. Incorporating low-importance sensors can, in fact, degrade reconstruction accuracy. These findings highlight the need for principled sensor importance evaluation and provide a scalable pathway for guiding sensor deployment in physics-informed inverse modeling.

Editorial analysis

A structured set of objections, weighed in public.

Desk editor's note, referee report, simulated authors' rebuttal, and a circularity audit. Tearing a paper down is the easy half of reading it; the pith above is the substance, this is the friction.

Referee Report

3 major / 3 minor

Summary. The manuscript proposes FOSSA, a post-training sensor selection method for PINN inverse problems. It computes per-sensor importance scores directly from the first-order optimality (stationarity) residual of the converged PINN loss after a single training run, avoiding the repeated retraining required by active-learning baselines. A refinement step is added to mitigate solver instability. On the inverse ECG problem the authors report that low-importance sensors can degrade reconstruction accuracy, providing a global ranking of candidate electrode locations.

Significance. If validated, the approach supplies a low-cost, global diagnostic for sensor utility in non-convex PINN inverse problems—an attractive alternative to iterative experimental-design loops. The ECG demonstration that “more sensors can hurt” is practically relevant for biomedical imaging where electrode placement is costly. The single-run character and explicit use of the optimality condition are clear methodological strengths, provided the scores are shown to predict actual marginal error changes.

major comments (3)
  1. [§3.2] §3.2 (importance-score definition): the score is extracted from the first-order stationarity condition evaluated at one converged point. Because the PINN loss is non-convex and the forward operator produces spatially correlated measurements, the marginal effect of adding or removing a sensor is generally a higher-order quantity. The manuscript must demonstrate, via leave-one-out or incremental retraining experiments, that low-scoring sensors actually increase reconstruction error and that the first-order ranking correlates with these changes.
  2. [§4] §4 (ECG experiments): the central claim that “incorporating low-importance sensors can degrade reconstruction accuracy” is load-bearing yet unsupported by the quantitative detail supplied in the abstract. The full manuscript must report concrete metrics—relative L2 error, RMSE, or correlation coefficients—with and without the low-importance subset, together with standard deviations over multiple random seeds or initializations and a direct comparison against random or greedy baselines.
  3. [§3.3] §3.3 (refinement scheme): the procedure for handling instability is described but its effect on the resulting importance scores is not quantified. An ablation showing score stability with and without refinement, and the number of additional forward/adjoint solves required, is needed to establish that the method remains practical and that the scores remain reliable.
minor comments (3)
  1. The abstract would be strengthened by including one or two key quantitative results (e.g., error reduction percentages) so that readers can immediately gauge the practical impact.
  2. [Notation] Notation for the per-sensor residual and the weighting of data-fidelity terms should be made fully explicit and cross-referenced to the PINN loss in Eq. (X).
  3. [Introduction] A short discussion of related sensor-selection literature in inverse problems (e.g., optimal experimental design for linear inverse problems) would help situate the contribution.

Simulated Author's Rebuttal

3 responses · 0 unresolved

We thank the referee for the thoughtful and constructive review. We appreciate the recognition of FOSSA's methodological strengths as a single-run, optimality-based diagnostic and the practical relevance of the ECG findings. We address each major comment below and will incorporate the requested validations and quantitative details in the revision.

read point-by-point responses
  1. Referee: §3.2 (importance-score definition): the score is extracted from the first-order stationarity condition evaluated at one converged point. Because the PINN loss is non-convex and the forward operator produces spatially correlated measurements, the marginal effect of adding or removing a sensor is generally a higher-order quantity. The manuscript must demonstrate, via leave-one-out or incremental retraining experiments, that low-scoring sensors actually increase reconstruction error and that the first-order ranking correlates with these changes.

    Authors: We agree that non-convexity and measurement correlations imply that first-order scores are an approximation whose predictive power for marginal error changes should be verified. The current manuscript provides supporting evidence through the observed degradation in ECG reconstructions when low-importance sensors are retained, but we acknowledge that direct correlation analysis via retraining would strengthen the validation. We will add leave-one-out and incremental retraining experiments on representative sensor subsets in the revised §4 (or a new appendix) to quantify error increases for low-scoring sensors and report Pearson/Spearman correlations between FOSSA scores and the resulting error deltas. revision: yes

  2. Referee: §4 (ECG experiments): the central claim that “incorporating low-importance sensors can degrade reconstruction accuracy” is load-bearing yet unsupported by the quantitative detail supplied in the abstract. The full manuscript must report concrete metrics—relative L2 error, RMSE, or correlation coefficients—with and without the low-importance subset, together with standard deviations over multiple random seeds or initializations and a direct comparison against random or greedy baselines.

    Authors: The manuscript reports quantitative reconstruction results in §4 that demonstrate degradation when low-importance sensors are included. To meet the referee's request for fuller detail, we will revise §4 to include explicit tables/figures with relative L2 errors, RMSE, and correlation coefficients comparing the full sensor set against the high-importance subset. We will also report standard deviations over multiple random seeds/initializations and add direct comparisons against random selection and a greedy active-learning baseline to benchmark performance. revision: yes

  3. Referee: §3.3 (refinement scheme): the procedure for handling instability is described but its effect on the resulting importance scores is not quantified. An ablation showing score stability with and without refinement, and the number of additional forward/adjoint solves required, is needed to establish that the method remains practical and that the scores remain reliable.

    Authors: We agree that quantifying the refinement's effect is necessary to confirm practicality and reliability. The refinement is a lightweight post-processing step to stabilize the stationarity residual. In the revision we will add an ablation in §3.3 comparing importance-score distributions, rankings, and variance with versus without refinement. We will also tabulate the average number of additional forward and adjoint solves incurred by the refinement across the ECG experiments, showing that the overhead remains modest while improving score stability. revision: yes

Circularity Check

0 steps flagged

No significant circularity detected

full rationale

The FOSSA method derives sensor importance scores directly from the first-order stationarity condition of the PINN loss evaluated at a single converged solution, then empirically validates on ECG data that low-scoring sensors can degrade reconstruction accuracy when included. This is a heuristic proposal rather than a self-definitional loop: the score is computed from the trained model's optimality residual, but the accuracy degradation claim is tested via separate subset experiments that are not forced by the score definition itself. No load-bearing self-citations, ansatzes smuggled via prior work, or fitted parameters renamed as independent predictions appear in the abstract or described chain. The derivation remains self-contained as an algorithmic contribution with external empirical checks.

Axiom & Free-Parameter Ledger

0 free parameters · 1 axioms · 0 invented entities

The approach rests on the assumption that a converged PINN satisfies first-order optimality and that this local condition can be linearly decomposed across sensor locations; no free parameters or new physical entities are introduced in the abstract.

axioms (1)
  • domain assumption A trained PINN has reached a stationary point where the first-order optimality condition holds for the composite loss.
    Invoked to justify using the optimality residual as an importance measure.

pith-pipeline@v0.9.0 · 5564 in / 1182 out tokens · 26434 ms · 2026-05-10T18:40:54.890342+00:00 · methodology

discussion (0)

Sign in with ORCID, Apple, or X to comment. Anyone can read and Pith papers without signing in.

Reference graph

Works this paper leans on

60 extracted references · 60 canonical work pages

  1. [1]

    The inverse problem of electrocardiography,

    A. J. Pullan, L. K. Cheng, M. P. Nash, A. Ghodrati, R. MacLeod, D. H. Brookset al., “The inverse problem of electrocardiography,” Comprehensive electrocardiology, vol. 1, pp. 299–344, 2010

  2. [2]

    Evaluation of inverse methods and head models for eeg source local- ization using a human skull phantom,

    S. Baillet, J. Riera, G. Marin, J. Mangin, J. Aubert, and L. Garnero, “Evaluation of inverse methods and head models for eeg source local- ization using a human skull phantom,”Physics in medicine & biology, vol. 46, no. 1, pp. 77–96, 2001

  3. [3]

    Finite element analysis of some inverse elasticity problems,

    A. Maniatty, N. Zabaras, and K. Stelson, “Finite element analysis of some inverse elasticity problems,”Journal of engineering mechanics, vol. 115, no. 6, pp. 1303–1317, 1989

  4. [4]

    Role of sensors in error propagation with the dynamic constrained observability method,

    T. Peng, M. Nogal, J. R. Casas, and J. Turmo, “Role of sensors in error propagation with the dynamic constrained observability method,” Sensors, vol. 21, no. 9, p. 2918, 2021

  5. [5]

    Noise, ill-conditioning and sensor placement analysis for force estimation through virtual sensing,

    T. Tamarozzi, E. Risaliti, W. Rottiers, W. Desmet, P. Sas, D. Moens, A. VanDeWalleet al., “Noise, ill-conditioning and sensor placement analysis for force estimation through virtual sensing,” inIn Interna- tional Conference on Noise and Vibration Engineering (ISMA2016),. Katholieke Univ Leuven, Dept Werktuigkunde, 2016, pp. 1741–1756

  6. [6]

    Solving inverse problems using data-driven models,

    S. Arridge, P. Maass, O. ¨Oktem, and C.-B. Sch ¨onlieb, “Solving inverse problems using data-driven models,”Acta numerica, vol. 28, pp. 1–174, 2019

  7. [7]

    Physics-informed neural networks: A deep learning framework for solving forward and inverse problems involving nonlinear partial differential equations,

    M. Raissi, P. Perdikaris, and G. E. Karniadakis, “Physics-informed neural networks: A deep learning framework for solving forward and inverse problems involving nonlinear partial differential equations,” Journal of Computational physics, vol. 378, pp. 686–707, 2019

  8. [8]

    Physics-informed neural networks and extensions

    M. Raissi, P. Perdikaris, N. Ahmadi, and G. E. Karniadakis, “Physics-informed neural networks and extensions,”arXiv preprint arXiv:2408.16806, 2024

  9. [9]

    Physics-informed machine learning,

    G. E. Karniadakis, I. G. Kevrekidis, L. Lu, P. Perdikaris, S. Wang, and L. Yang, “Physics-informed machine learning,”Nature Reviews Physics, vol. 3, no. 6, pp. 422–440, 2021

  10. [10]

    On the use of fourier features-physics in- formed neural networks (ff-pinn) for forward and inverse fluid mechanics problems,

    O. Sallam and M. F ¨urth, “On the use of fourier features-physics in- formed neural networks (ff-pinn) for forward and inverse fluid mechanics problems,”Proceedings of the Institution of Mechanical Engineers, Part M: Journal of Engineering for the Maritime Environment, vol. 237, no. 4, pp. 846–866, 2023

  11. [12]

    Physics- informed neural networks for heat transfer problems,

    S. Cai, Z. Wang, S. Wang, P. Perdikaris, and G. E. Karniadakis, “Physics- informed neural networks for heat transfer problems,”Journal of Heat Transfer, vol. 143, no. 6, p. 060801, 2021

  12. [13]

    Solving inverse heat transfer problems without surrogate models: a fast, data-sparse, physics informed neural network approach,

    V . Oommen and B. Srinivasan, “Solving inverse heat transfer problems without surrogate models: a fast, data-sparse, physics informed neural network approach,”Journal of Computing and Information Science in Engineering, vol. 22, no. 4, p. 041012, 2022

  13. [14]

    Physics-informed neural networks (pinns) for wave propagation and full waveform inversions,

    M. Rasht-Behesht, C. Huber, K. Shukla, and G. E. Karniadakis, “Physics-informed neural networks (pinns) for wave propagation and full waveform inversions,”Journal of Geophysical Research: Solid Earth, vol. 127, no. 5, p. e2021JB023120, 2022

  14. [15]

    Pinns for medical image analysis: a survey,

    C. Banerjee, K. Nguyen, O. Salvado, T. Tran, and C. Fookes, “Pinns for medical image analysis: a survey,”arXiv preprint arXiv:2408.01026, 2024

  15. [16]

    Physics-constrained deep learning for robust inverse ecg modeling,

    J. Xie and B. Yao, “Physics-constrained deep learning for robust inverse ecg modeling,”IEEE Transactions on Automation Science and Engineering, vol. 20, no. 1, pp. 151–166, 2022

  16. [17]

    Can-pinn: A fast physics-informed neural network based on coupled-automatic– 12 numerical differentiation method,

    P.-H. Chiu, J. C. Wong, C. Ooi, M. H. Dao, and Y .-S. Ong, “Can-pinn: A fast physics-informed neural network based on coupled-automatic– 12 numerical differentiation method,”Computer Methods in Applied Me- chanics and Engineering, vol. 395, p. 114909, 2022

  17. [18]

    Random sampling via sensor networks: Estimation accuracy vs. energy consumption,

    F. Zabini, A. Calisti, D. Dardari, and A. Conti, “Random sampling via sensor networks: Estimation accuracy vs. energy consumption,” in2016 24th European Signal Processing Conference (EUSIPCO). IEEE, 2016, pp. 130–134

  18. [19]

    Minimax and maximin distance designs,

    M. E. Johnson, L. M. Moore, and D. Ylvisaker, “Minimax and maximin distance designs,”Journal of statistical planning and inference, vol. 26, no. 2, pp. 131–148, 1990

  19. [20]

    Active learning with physics-informed neural networks for optimal sensor placement in deep tunneling through transversely isotropic elastic rocks,

    A. Tristani and C. Arson, “Active learning with physics-informed neural networks for optimal sensor placement in deep tunneling through transversely isotropic elastic rocks,”arXiv preprint arXiv:2511.20574, 2025

  20. [21]

    Active learning based sampling for high- dimensional nonlinear partial differential equations,

    W. Gao and C. Wang, “Active learning based sampling for high- dimensional nonlinear partial differential equations,”Journal of Com- putational Physics, vol. 475, p. 111848, 2023

  21. [22]

    Physics-constrained deep active learning for spa- tiotemporal modeling of cardiac electrodynamics,

    J. Xie and B. Yao, “Physics-constrained deep active learning for spa- tiotemporal modeling of cardiac electrodynamics,”Computers in Biology and Medicine, vol. 146, p. 105586, 2022

  22. [23]

    Optimal sensor placement for digital twin based on mutual information and correlation with multi-fidelity data,

    S. Wang, X. Lai, X. He, K. Li, L. Lv, and X. Song, “Optimal sensor placement for digital twin based on mutual information and correlation with multi-fidelity data,”Engineering with Computers, vol. 40, no. 2, pp. 1289–1308, 2024

  23. [24]

    Development of the senseiver for efficient field reconstruction from sparse observations,

    J. E. Santos, Z. R. Fox, A. Mohan, D. O’Malley, H. Viswanathan, and N. Lubbers, “Development of the senseiver for efficient field reconstruction from sparse observations,”Nature Machine Intelligence, vol. 5, no. 11, pp. 1317–1325, 2023

  24. [25]

    Super-resolution and uncertainty estimation from sparse sensors of dynamical physical systems,

    A. M. Collins, P. Rivera-Casillas, S. Dutta, O. M. Cecil, A. C. Trautz, and M. W. Farthing, “Super-resolution and uncertainty estimation from sparse sensors of dynamical physical systems,”Frontiers in Water, vol. 5, p. 1137110, 2023

  25. [26]

    Understanding physics- informed neural networks: Techniques, applications, trends, and chal- lenges,

    A. Farea, O. Yli-Harja, and F. Emmert-Streib, “Understanding physics- informed neural networks: Techniques, applications, trends, and chal- lenges,”Ai, vol. 5, no. 3, pp. 1534–1557, 2024

  26. [27]

    Physr: Physics-informed deep super-resolution for spatiotemporal data,

    P. Ren, C. Rao, Y . Liu, Z. Ma, Q. Wang, J.-X. Wang, and H. Sun, “Physr: Physics-informed deep super-resolution for spatiotemporal data,” Journal of Computational Physics, vol. 492, p. 112438, 2023

  27. [28]

    Physics- informed neural networks (pinns) for fluid mechanics: A review,

    S. Cai, Z. Mao, Z. Wang, M. Yin, and G. E. Karniadakis, “Physics- informed neural networks (pinns) for fluid mechanics: A review,”Acta Mechanica Sinica, vol. 37, no. 12, pp. 1727–1738, 2021

  28. [29]

    Hidden fluid mechanics: Learning velocity and pressure fields from flow visualizations,

    M. Raissi, A. Yazdani, and G. E. Karniadakis, “Hidden fluid mechanics: Learning velocity and pressure fields from flow visualizations,”Science, vol. 367, no. 6481, pp. 1026–1030, 2020

  29. [30]

    Machine learning in fluid dynamics—physics-informed neural networks (pinns) using sparse data: A review,

    M. Ali, P. Miron, M. M ¨onnigmann, B. Nikolayet al., “Machine learning in fluid dynamics—physics-informed neural networks (pinns) using sparse data: A review,”Fluids, vol. 10, no. 9, p. 226, 2025

  30. [31]

    Physics-informed residual learning with spatiotemporal local support for inverse ecg reconstruction,

    L. Zhu, K. Bilchick, and J. Xie, “Physics-informed residual learning with spatiotemporal local support for inverse ecg reconstruction,”Scientific Reports, vol. 15, no. 1, p. 31747, 2025

  31. [32]

    Physics-informed neural networks for physiological signal processing and modeling: a narrative review,

    A. Zhao, D. Fattahi, and X. Hu, “Physics-informed neural networks for physiological signal processing and modeling: a narrative review,” Physiological measurement, vol. 46, no. 7, p. 07TR02, 2025

  32. [33]

    A physics-informed deep learning framework for inversion and surrogate modeling in solid mechanics,

    E. Haghighat, M. Raissi, A. Moure, H. Gomez, and R. Juanes, “A physics-informed deep learning framework for inversion and surrogate modeling in solid mechanics,”Computer Methods in Applied Mechanics and Engineering, vol. 379, p. 113741, 2021

  33. [34]

    Physics-aware machine learning for computational fluid dynamics surrogate model to estimate ventilation performance,

    M. Kim, N.-K. Chau, S. Park, P. C. Nguyen, S. S. Baek, and S. Choi, “Physics-aware machine learning for computational fluid dynamics surrogate model to estimate ventilation performance,”Physics of Fluids, vol. 37, no. 2, 2025

  34. [35]

    Parcv2: Physics-aware recurrent convolutional neural networks for spatiotemporal dynamics modeling,

    P. C. Nguyen, X. Cheng, S. Azarfar, P. Seshadri, Y . T. Nguyen, M. Kim, S. Choi, H. Udaykumar, and S. Baek, “Parcv2: Physics-aware recurrent convolutional neural networks for spatiotemporal dynamics modeling,” arXiv preprint arXiv:2402.12503, 2024

  35. [36]

    A-pinn: Auxiliary physics informed neural networks for forward and inverse problems of nonlinear integro-differential equations,

    L. Yuan, Y .-Q. Ni, X.-Y . Deng, and S. Hao, “A-pinn: Auxiliary physics informed neural networks for forward and inverse problems of nonlinear integro-differential equations,”Journal of Computational Physics, vol. 462, p. 111260, 2022

  36. [37]

    Application of physics-informed neural networks to inverse problems in unsaturated groundwater flow,

    I. Depina, S. Jain, S. Mar Valsson, and H. Gotovac, “Application of physics-informed neural networks to inverse problems in unsaturated groundwater flow,”Georisk: Assessment and Management of Risk for Engineered Systems and Geohazards, vol. 16, no. 1, pp. 21–36, 2022

  37. [38]

    Physics-informed neural networks for inverse electromagnetic problems,

    M. Baldan, P. Di Barba, and D. A. Lowther, “Physics-informed neural networks for inverse electromagnetic problems,”IEEE Transactions on Magnetics, vol. 59, no. 5, pp. 1–5, 2023

  38. [39]

    Ep-pinns: Cardiac electrophysiology characterisation using physics-informed neural networks,

    C. Herrero Martin, A. Oved, R. A. Chowdhury, E. Ullmann, N. S. Peters, A. A. Bharath, and M. Varela, “Ep-pinns: Cardiac electrophysiology characterisation using physics-informed neural networks,”Frontiers in Cardiovascular Medicine, vol. 8, p. 768419, 2022

  39. [40]

    Meta-learning physics-informed neural networks for personalized cardiac modeling,

    M. Toloubidokhti, R. Missel, S. Lian, and L. Wang, “Meta-learning physics-informed neural networks for personalized cardiac modeling,” in International Conference on Medical Image Computing and Computer- Assisted Intervention. Springer, 2025, pp. 344–354

  40. [41]

    Solving the inverse problem of electrocardiography for cardiac digital twins: A survey,

    L. Li, J. Camps, B. Rodriguez, and V . Grau, “Solving the inverse problem of electrocardiography for cardiac digital twins: A survey,” IEEE Reviews in Biomedical Engineering, vol. 18, pp. 316–336, 2024

  41. [42]

    A physics- driven sensor placement optimization methodology for temperature field reconstruction,

    X. Liu, W. Yao, W. Peng, Z. Fu, Z. Xiang, and X. Chen, “A physics- driven sensor placement optimization methodology for temperature field reconstruction,”Applied Thermal Engineering, vol. 257, p. 124476, 2024

  42. [43]

    Examining the robustness of physics-informed neural net- works to noise for inverse problems,

    A. Jekic, A. Natsaridou, S. Riemer-Sørensen, H. Langseth, and O. E. Gundersen, “Examining the robustness of physics-informed neural net- works to noise for inverse problems,”arXiv preprint arXiv:2509.20191, 2025

  43. [44]

    Optimal experimental design: Formulations and computations,

    X. Huan, J. Jagalur, and Y . Marzouk, “Optimal experimental design: Formulations and computations,”Acta Numerica, vol. 33, pp. 715–840, 2024

  44. [45]

    Data-driven sparse sensor placement for reconstruction: Demonstrating the benefits of exploiting known patterns,

    K. Manohar, B. W. Brunton, J. N. Kutz, and S. L. Brunton, “Data-driven sparse sensor placement for reconstruction: Demonstrating the benefits of exploiting known patterns,”IEEE Control Systems Magazine, vol. 38, no. 3, pp. 63–86, 2018

  45. [46]

    T. J. Santner, B. J. Williams, W. I. Notz, and B. J. Williams,The design and analysis of computer experiments. Springer, 2003, vol. 1

  46. [47]

    Approximately uniform random sampling in sensor networks,

    B. A. Bash, J. W. Byers, and J. Considine, “Approximately uniform random sampling in sensor networks,” inProceeedings of the 1st international workshop on Data management for sensor networks: in conjunction with VLDB 2004, 2004, pp. 32–39

  47. [48]

    Sensor selection via randomized sampling,

    S. D. Bopardikar, “Sensor selection via randomized sampling,”arXiv preprint arXiv:1712.06511, 2017

  48. [49]

    Minimax and maximin space-filling designs: some prop- erties and methods for construction,

    L. Pronzato, “Minimax and maximin space-filling designs: some prop- erties and methods for construction,”Journal de la Soci ´et´e Franc ¸aise de Statistique, vol. 158, no. 1, pp. 7–36, 2017

  49. [50]

    A cluster analysis approach to sampling domestic properties for sensor deployment,

    T. Menneer, M. Mueller, and S. Townley, “A cluster analysis approach to sampling domestic properties for sensor deployment,”Building and Environment, vol. 231, p. 110032, 2023

  50. [51]

    Optimized clustering algorithms for large wireless sensor networks: A review,

    D. Wohwe Sambo, B. O. Yenke, A. F ¨orster, and P. Dayang, “Optimized clustering algorithms for large wireless sensor networks: A review,” Sensors, vol. 19, no. 2, p. 322, 2019

  51. [52]

    Dynamic cluster head selection method for wireless sensor network,

    D. Jia, H. Zhu, S. Zou, and P. Hu, “Dynamic cluster head selection method for wireless sensor network,”IEEE Sensors Journal, vol. 16, no. 8, pp. 2746–2754, 2015

  52. [53]

    Maximum mutual information principle for dynamic sensor query problems,

    E. Ertin, J. W. Fisher, and L. C. Potter, “Maximum mutual information principle for dynamic sensor query problems,” inInformation processing in sensor networks. Springer, 2003, pp. 405–416

  53. [54]

    Sensor selection via maximizing hybrid bayesian fisher information and mutual information in unreliable sensor net- works,

    Q. Yan and J. Chen, “Sensor selection via maximizing hybrid bayesian fisher information and mutual information in unreliable sensor net- works,”Electronics, vol. 9, no. 2, p. 283, 2020

  54. [55]

    Temperature optimization of metal oxide sensor arrays using mutual information,

    J. Fonollosa, L. Fern ´andez, R. Huerta, A. Guti ´errez-G´alvez, and S. Marco, “Temperature optimization of metal oxide sensor arrays using mutual information,”Sensors and Actuators B: Chemical, vol. 187, pp. 331–339, 2013

  55. [56]

    Deepxde: A deep learning library for solving differential equations,

    L. Lu, X. Meng, Z. Mao, and G. E. Karniadakis, “Deepxde: A deep learning library for solving differential equations,”SIAM review, vol. 63, no. 1, pp. 208–228, 2021

  56. [57]

    A comprehensive study of non-adaptive and residual-based adaptive sampling for physics- informed neural networks,

    C. Wu, M. Zhu, Q. Tan, Y . Kartha, and L. Lu, “A comprehensive study of non-adaptive and residual-based adaptive sampling for physics- informed neural networks,”Computer Methods in Applied Mechanics and Engineering, vol. 403, p. 115671, 2023

  57. [58]

    Pied: Physics-informed experimental design for inverse problems,

    A. Hemachandra, G. K. R. Lau, S.-K. Ng, and B. K. H. Low, “Pied: Physics-informed experimental design for inverse problems,”arXiv preprint arXiv:2503.07070, 2025

  58. [59]

    Physics-informed neural networks for solving forward and inverse problems in complex beam systems,

    T. Kapoor, H. Wang, A. N ´u˜nez, and R. Dollevoet, “Physics-informed neural networks for solving forward and inverse problems in complex beam systems,”IEEE Transactions on Neural Networks and Learning Systems, vol. 35, no. 5, pp. 5981–5995, 2023

  59. [60]

    Spatiotemporal regularization for inverse ecg mod- eling,

    B. Yao and H. Yang, “Spatiotemporal regularization for inverse ecg mod- eling,”IISE Transactions on Healthcare Systems Engineering, vol. 11, no. 1, pp. 11–23, 2020

  60. [61]

    Relating epicardial to body surface potential distributions by means of transfer coefficients based on geometry measurements,

    R. C. Barr, M. Ramsey, and M. S. Spach, “Relating epicardial to body surface potential distributions by means of transfer coefficients based on geometry measurements,”IEEE Transactions on biomedical engineering, no. 1, pp. 1–11, 2007