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arxiv: 2606.30764 · v1 · pith:LV2Q4FKZnew · submitted 2026-06-29 · 🌌 astro-ph.HE · astro-ph.GA

Active Galactic Nuclei as high-energy neutrino sources

Pith reviewed 2026-07-01 02:00 UTC · model grok-4.3

classification 🌌 astro-ph.HE astro-ph.GA
keywords active galactic nucleihigh-energy neutrinosIceCubeblazarsneutrino sourcesmulti-messenger astronomyTXS 0506+056NGC 1068
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The pith

IceCube reports neutrino events possibly linked to both the radio-loud AGN TXS 0506+056 and the radio-quiet AGN NGC 1068, though the gamma-ray blazar population accounts for only a small fraction of the total astrophysical neutrino flux.

A machine-rendered reading of the paper's core claim, the machinery that carries it, and where it could break.

This review surveys searches for correlations between IceCube high-energy neutrinos and active galactic nuclei. It emphasizes that the gamma-ray blazar population contributes only a minor share of the observed neutrino flux. Possible individual associations are discussed for TXS 0506+056 and NGC 1068, along with other claimed blazar links that remain controversial. Neutrino production mechanisms proposed for these objects are examined, and the paper outlines open questions for upcoming facilities and multi-messenger observations.

Core claim

The IceCube Collaboration has reported high-energy neutrino events that may come from both the radio-loud AGN TXS 0506+056 and the radio-quiet AGN NGC 1068, while the gamma-ray blazar population accounts for only a small fraction of the total astrophysical neutrino flux. Other possible associations between neutrino events and individual blazars have been claimed with mixed results. The properties of these sources and different neutrino production mechanisms are discussed.

What carries the argument

Spatial and temporal correlations between individual high-energy neutrino events and the sky positions of specific AGN, together with models of neutrino production in AGN jets or coronae.

If this is right

  • Individual AGN such as TXS 0506+056 and NGC 1068 could contribute measurably to the neutrino flux even if the full blazar population does not.
  • Neutrino production may occur through distinct channels in radio-loud jets versus radio-quiet environments.
  • Multi-frequency monitoring combined with neutrino alerts will be required to test these candidate sources.
  • Future neutrino observatories will help determine whether AGN dominate the remaining unexplained portion of the astrophysical flux.

Where Pith is reading between the lines

These are editorial extensions of the paper, not claims the author makes directly.

  • If the associations hold, radio-quiet AGN may represent a previously under-appreciated channel for high-energy neutrino production independent of strong jets.
  • Confirmation would strengthen the case that AGN also accelerate a fraction of ultra-high-energy cosmic rays, linking neutrino and cosmic-ray observations.
  • Population-level limits on blazars would then direct attention toward other AGN subclasses or entirely different source classes for the bulk of the flux.

Load-bearing premise

The reported spatial and temporal coincidences between neutrino events and specific AGN reflect genuine physical associations rather than chance alignments or background fluctuations.

What would settle it

A statistical analysis demonstrating that the probability of the observed neutrino-AGN coincidences arising from background alone exceeds the significance level reported by IceCube would refute the proposed associations.

read the original abstract

Identifying the sources of the high-energy astrophysical neutrinos has been one of the main topics in astrophysics since the first observation of high-energy neutrinos by the IceCube Neutrino Observatory. Active Galactic Nuclei (AGN) are sources of high-energy gamma-rays and are considered to be promising candidates to be sources of high-energy neutrinos and ultra-high energy cosmic rays as well. However, several studies suggest that the neutrino emission from the $\gamma$-ray blazar population only accounts for a small fraction of the total astrophysical neutrino flux. We present and discuss recent results on the search for correlations between astrophysical neutrinos and both gamma-ray and radio bright AGN. The IceCube Collaboration has reported high-energy neutrino events that may come from both the radio-loud AGN TXS 0506+056 and the radio-quiet AGN NGC 1068. Other cases of possible associations between high-energy neutrino events and individual blazars were claimed with controversial results. We discuss the properties of these sources together with the different neutrino production mechanisms proposed for those sources. Finally, we outline future prospects in the field, focusing on remaining open questions, the development of upcoming neutrino facilities, and the evolving multi-frequency landscape within the multi-messenger era.

Editorial analysis

A structured set of objections, weighed in public.

Desk editor's note, referee report, simulated authors' rebuttal, and a circularity audit. Tearing a paper down is the easy half of reading it; the pith above is the substance, this is the friction.

Referee Report

0 major / 2 minor

Summary. The manuscript is a review summarizing IceCube observations of high-energy astrophysical neutrinos and their possible associations with Active Galactic Nuclei (AGN). It highlights candidate sources including the radio-loud blazar TXS 0506+056 and the radio-quiet Seyfert galaxy NGC 1068, notes that the gamma-ray blazar population accounts for only a small fraction of the total neutrino flux based on population studies, discusses proposed neutrino production mechanisms, and outlines future prospects with upcoming facilities in the multi-messenger context.

Significance. As a synthesis of recent multi-messenger results, the review provides a useful overview of an active research area, correctly employing cautious language regarding individual source associations and emphasizing the limited blazar contribution. It draws attention to open questions without introducing new claims, derivations, or statistical tests.

minor comments (2)
  1. [Abstract] Abstract: The statement 'We present and discuss recent results on the search for correlations' could be rephrased to explicitly note that the work is a review summarizing published IceCube findings and external population studies rather than reporting new analyses or data.
  2. The manuscript would benefit from a dedicated section or table listing the key IceCube events, their energies, and the specific AGN associations discussed, to improve readability for readers unfamiliar with the cited reports.

Simulated Author's Rebuttal

0 responses · 0 unresolved

We thank the referee for their positive assessment of the manuscript and for recommending acceptance. The referee's summary correctly reflects the scope of the review as a synthesis of IceCube results on AGN-neutrino associations, population constraints, and future prospects.

Circularity Check

0 steps flagged

No significant circularity; review contains no derivations

full rationale

The manuscript is a review summarizing external IceCube reports and population studies on AGN-neutrino associations. It presents no equations, fitted parameters, predictions, or new statistical claims; all statements use cautious language and cite external results. No load-bearing step reduces by construction to inputs, self-citations, or ansatzes. The paper is self-contained against external benchmarks.

Axiom & Free-Parameter Ledger

0 free parameters · 0 axioms · 0 invented entities

This is a review paper; the abstract introduces no new free parameters, axioms, or invented entities.

pith-pipeline@v0.9.1-grok · 5746 in / 1137 out tokens · 47434 ms · 2026-07-01T02:00:33.351571+00:00 · methodology

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Works this paper leans on

300 extracted references · 126 canonical work pages · 43 internal anchors

  1. [1]

    G., Abbasi, R., Abdouand, Y., et al

    Aartsen, M. G., Abbasi, R., Abdouand, Y., et al. 2013, Science, 342, 1242856

  2. [2]

    G., Abraham, K., Ackermann, M, et al

    Aartsen, M. G., Abraham, K., Ackermann, M, et al. 2017, ApJ, 835, 151

  3. [3]

    Aartsen, M. G. Ackermann, M.; Adams, J., et al. 2017, APh, 92, 30

  4. [4]

    G., Abbasi, R., Abdouand, Y., et al

    Aartsen, M. G., Abbasi, R., Abdouand, Y., et al. 2018, Science, 361, 147

  5. [5]

    G., Ackermann, M., Adams, J., et al

    Aartsen, M. G., Ackermann, M., Adams, J., et al. 2018, PhRvD, 98, 062003

  6. [6]

    G., Ackermann, M., Adams, J., et al

    Aartsen, M. G., Ackermann, M., Adams, J., et al. 2020, PhRvL, 124, 1103

  7. [7]

    G., Abbasi, R., Ackermann, M., et al

    Aartsen, M. G., Abbasi, R., Ackermann, M., et al. 2021, JPhG, 48f0501

  8. [8]

    G., Ackermann, M., Adams, J., et al

    Aartsen, M. G., Ackermann, M., Adams, J., et al. 2023, Science, 380, 1338

  9. [9]

    2021, PhRvD, 104, 2002

    Abbasi, R., Ackermann, M., Adams, J., et al. 2021, PhRvD, 104, 2002

  10. [10]

    2022, ApJ, 928, 50

    Abbasi, R., Ackermann, M., Adams, J., et al. 2022, ApJ, 928, 50

  11. [11]

    2022, Science, 378, 538

    Abbasi, R., Ackermann, M., Adams, J., et al. 2022, Science, 378, 538

  12. [12]

    2023, ApJ, 954, 75

    Abbasi, R., Ackermann, M., Adams, J., et al. 2023, ApJ, 954, 75

  13. [13]

    2023, ApJS, 269, 25

    Abbasi, R., Ackermann, M., Adams, J., et al. 2023, ApJS, 269, 25

  14. [14]

    2023, Science, 380, 1338

    Abbasi, R., Ackermann, M., Adams, J., et al. 2023, Science, 380, 1338

  15. [15]

    2023, ApJ, 951, 45

    Abbasi, R., Ackermann, M., Adams, J., et al. 2023, ApJ, 951, 45

  16. [16]

    2024, ApJ, 973, 97

    Abbasi, R., Ackermann, M., Adams, J., et al. 2024, ApJ, 973, 97

  17. [17]

    2025, 988, 141

    Abbasi, R, Ackermann, M., Adams, J., et al. 2025, 988, 141

  18. [18]

    U., Albert, A., Alfaro, R., et al

    Abeysekara, A. U., Albert, A., Alfaro, R., et al. 2017, ApJ, 843, 39

  19. [19]

    Biland, A, Brand, K., et al

    Abhir, J. Biland, A, Brand, K., et al. 2025, submitted to ApJ, arXiv:2512.16562

  20. [20]

    A., Ansoldi, S., Antonelli, L

    Acciari, V. A., Ansoldi, S., Antonelli, L. A., et al. 2019, ApJ, 883, 135

  21. [21]

    A., Aniello, T., Ansoldi, S., et al 2022, ApJ, 927, 197

    Acciari, V. A., Aniello, T., Ansoldi, S., et al 2022, ApJ, 927, 197

  22. [22]

    S., Agudo, I., Samarai, Al., et al

    Acharya, B. S., Agudo, I., Samarai, Al., et al. 2019, World Scientific book

  23. [23]

    2016, Journal of Physics G: Nuclear and Particle Physics, 43, 8, 084001

    Adrian-Martinez, S., Ageron, M., Aharonian, F., et al. 2016, Journal of Physics G: Nuclear and Particle Physics, 43, 8, 084001

  24. [24]

    Aiello, S., Albert, A., et al

    Adriani, O. Aiello, S., Albert, A., et al. 2025, ApJL, 984, 2

  25. [25]

    A., Al Samarai, I., et al

    Ageron, M., Aguilar, J. A., Al Samarai, I., et al. 2011, NIMA, 656, 11

  26. [26]

    A., Allison, P., Beatty, J

    Aguilar, J. A., Allison, P., Beatty, J. J., et al. 2021, Journal of Instrumentation, 16, P03025

  27. [27]

    G., Bazer-Bachi, A

    Aharonina, F., Akhperjanian, A. G., Bazer-Bachi, A. R., et al. 2006, A&A, 457, 899

  28. [28]

    2021, Chin

    Aharonian, F., An, Q., Axikegu, et al. 2021, Chin. Phys. C, 45, 025002

  29. [29]

    N., Bai, X, et al

    Ahrens, J., Bahcall, J. N., Bai, X, et al. 2004, APh, 20, 507

  30. [30]

    R., et al

    Aiello, S., Albert A., Alhebsi, A. R., et al. 2025, Science, 638, 376

  31. [31]

    2021, JCAP, 01, 064

    Albert, A., Andre, M., Anghinolfi, M., et al. 2021, JCAP, 01, 064

  32. [32]

    A., Antonelli, L

    Aleksic J., Alvarez, E. A., Antonelli, L. A., et al. 2012, APh, 35, 435

  33. [33]

    A., Avrorin, A

    Allakhverdyan, V. A., Avrorin, A. D., Avrorin, A. V., et al. 2024, MNRAS, 527, 8784

  34. [34]

    Y., Venturi, T., et al

    An, T., Hong, X. Y., Venturi, T., et al. 2004, A\ A, 421, 389

  35. [35]

    A., Arcaro, C., et al

    Ansoldi, S., Antonelli, L. A., Arcaro, C., et al. 2018, ApJ, 863, L10 \

  36. [36]

    Atoyan, A., & Dermer, C. D. 2001, PhRvL, 87, 221102

  37. [37]

    , Cordier, B., Wei, J

    Atteia, J.-L. , Cordier, B., Wei, J. 2022, IJMPD, 313008

  38. [38]

    B., Abdo, A

    Atwood, W. B., Abdo, A. A., Ackermann, M., et al. 2009, ApJ, 697, 1071

  39. [39]

    2015, 800L, 27

    Ajello, M., Gasparrini, D., Sanchez-Conde, M., et al. 2015, 800L, 27

  40. [40]

    2020, ApJ, 892, 105

    Ajello, M., Angioni, R., Axelsson, M., et al. 2020, ApJ, 892, 105

  41. [41]

    2022, ApJS, 263, 24

    Ajello, M., Baldini, L., Ballet, J., et al. 2022, ApJS, 263, 24

  42. [42]

    Becker Tjus, J., Eichmann, B., Halzen, F.; Kheirandish, A.; Saba, S. M

  43. [43]

    2022, ApJ, 941, L25

    Becker Tjus, J., Jaroschewski, I., Ghorbanietemad, A., et al. 2022, ApJ, 941, L25

  44. [44]

    2023, ApJ, 955, L32

    Bellenghi, C., Padovani, P., Resconi, E., Giommi, P. 2023, ApJ, 955, L32

  45. [45]

    2014, JInst, 9, P0012

    Biland, A., Bretz, T., Buss, J., et al. 2014, JInst, 9, P0012

  46. [46]

    2014, Nuclear Physics 3 Proceedings Supplements 256, 9

    Blandford, R., Simeon, P., Yuan, Y. 2014, Nuclear Physics 3 Proceedings Supplements 256, 9

  47. [47]

    2013, ApJ, 768, 54

    Bottcher, M., Reimer, A., Sweeney, K., Prakash, A. 2013, ApJ, 768, 54

  48. [48]

    , Bourke, T., Green, J

    Braun, R. , Bourke, T., Green, J. A., et al. 2015, Proceedings of Advancing Astrophysics with the Square Kilometre Array (AASKA14), 174

  49. [49]

    Buson, S., Tramacere, A., Oswald, L., et al., 2022, ApJ, 933, L43

  50. [50]

    A., et al

    Caputo, R., Ajello, M., Kierans, C. A., et al. 2022, JATIS, 8, 044003

  51. [51]

    2015, MNRAS,448, 910

    Cerruti, M.; Zech, A.; Boisson, C., et al. 2015, MNRAS,448, 910

  52. [52]

    P., Werner, M., Akeson, R., et al

    Crill, B. P., Werner, M., Akeson, R., et al. 2020, Proceedings of the SPIE, 11443E, 0I

  53. [53]

    2025, Nature Astronomy, 9, 36

    Cruise, M., Guainazzi, M., Aird, J., et al. 2025, Nature Astronomy, 9, 36

  54. [54]

    S., Barrett, J., Blackburn, L., et al

    Doeleman, S. S., Barrett, J., Blackburn, L., et al. 2023, Galaxies, 11, 10

  55. [55]

    A., Suvorova, O., Baikal-GVD Collaboration 2021, the Astronomer's Telegram, 15112, 1

    Dzhilkibaev, Z. A., Suvorova, O., Baikal-GVD Collaboration 2021, the Astronomer's Telegram, 15112, 1

  56. [56]

    2024, A&A, 684, A11

    Eppel, F., Kadler, M., Hessdorfer, J., et al. 2024, A&A, 684, A11

  57. [57]

    L., & Riley, J

    Fanaroff, B. L., & Riley, J. M. 1974, MNRAS, 167, 31

  58. [58]

    2017, in International Cosmic Ray Conference, Vol

    Fang, K., Alvarez-Muniz, J., Alves Batista, R., et al. 2017, in International Cosmic Ray Conference, Vol. 301, 35th International Cosmic Ray Conference (ICRC2017), 996

  59. [59]

    S., Halzen, F

    Fang, K., Gallagher, J. S., Halzen, F. 2022, ApJ, 933, 109

  60. [60]

    Fang, K., Lopez Rodriguez, E., Halzen, F., Gallagher, J. S. 2023, ApJ, 956, 8

  61. [61]

    2022, ATel, 15290, 1

    Filippini, F., Illuminati, G., Heijboer, A., et al. 2022, ATel, 15290, 1

  62. [62]

    G., Petropoulou, M., Comisso, L., et al

    Fiorillo, F. G., Petropoulou, M., Comisso, L., et al. 2024, ApJ, 961, L14

  63. [63]

    G., Testagrossa, F., Petropoulou

    Fiorillo, F. G., Testagrossa, F., Petropoulou. M., Winter, W. 2025, ApJ, 986, 1

  64. [64]

    T., Honscheid, K., et al

    Flaugher, B., Diehl, H. T., Honscheid, K., et al. 2015, ApJ, 150, 150

  65. [65]

    2020, ApJ, 893, 162

    Franckowiak, A., Garrappa, S., Paliya, V., et al. 2020, ApJ, 893, 162

  66. [66]

    F., Baum, S

    Gallimore, J. F., Baum, S. A., O?Dea, C. P. 2004, ApJ, 613, 794

  67. [67]

    Gao, S., Pohl, M., & Winter, W., 2017, ApJ, 843, 109

  68. [68]

    Garcia-Burillo, S., Combes, F., Ramos Almeida, C. et al. 2016, ApJL, 823, L12

  69. [69]

    Garcia-Burillo, S., Combes, F., Ramos Almeida, C. et al. 2019, A&A, 632, A61

  70. [70]

    2019, ApJ, 880, 103

    Garrappa, S., Buson, S., Franckoviak, A., et al. 2019, ApJ, 880, 103

  71. [71]

    Garrappa, S., Buson, S., 2020, , GCN, 26669

  72. [72]

    2004, ApJ, 611, 1005

    Gehrels, N., Chincarini, G., Giommi, P., et al. 2004, ApJ, 611, 1005

  73. [73]

    2005, A&A, 432, 401

    Ghisellini, G., Tavecchio, F., Chiaberge, M. 2005, A&A, 432, 401

  74. [74]

    2009, MNRAS, 397, 985

    Ghisellini, G., Tavecchio, F. 2009, MNRAS, 397, 985

  75. [75]

    2011, MNRAS, 414, 2674

    Ghisellini, G., Tavecchio, F., Foschini, L., Ghirlanda, G. 2011, MNRAS, 414, 2674

  76. [76]

    2017, MNRAS, 469, 255

    Ghisellini, G., Righi, C., Costamante, L., Tavecchio, F. 2017, MNRAS, 469, 255

  77. [77]

    E., Kim, D

    Gianolli, V. E., Kim, D. E., Bianchi, S., et al. 2023, MNRAS 523, 4468

  78. [78]

    2020, A&A, 640, L9

    Giommi, P., Padovani, P., Oikonomou, F., et al. 2020, A&A, 640, L9

  79. [79]

    1960, Anual Review Nuclear Science, 10, 63

    Greisen, K. 1960, Anual Review Nuclear Science, 10, 63

  80. [80]

    A., Craig, W

    Harrison, F. A., Craig, W. W., Christensen, F. E., et al. 2013, ApJ, 770, 103

Showing first 80 references.