Birational geometry of Fano hypersurfaces of index two

We prove that every non-trivial structure of a rationally connected fibre space (and so every structure of a Mori-Fano fibre space) on a general (in the sense of Zariski topology) hypersurface of degree $M$ in the $(M+1)$-dimensional projective space for $M\geq 14$ is given by a pencil of hyperplane sections. In particular, the variety $V$ is non-rational and its group of birational self-maps coincide with the group of biregular automorphisms and is therefore trivial. The proof is based on the techniques of the method of maximal singularities and the inversion of adjunction.