A new methodology which uses a mathematical procedure and pure substances for the determination of a TXRF spectrometer sensitivity curve

The usual method for determining the sensitivity curve of a TXRF spectrometer relies on calibration using a set of vendor-certified concentration values of reference calibration standards. These samples, which are certified by the provider, are costly and their quality cannot be verified. We propose the use of pure substances for calibration, along with a mathematical procedure, that assures a high precision and accuracy of the results. The method described herein is economically efficient and eliminates having to deal with some uncertainties related to the concentration of the standard used in the usual method, thereby improving the quality of the TXRF results.