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arxiv: 1508.04453 · v1 · pith:GFN2HQ7Hnew · submitted 2015-08-17 · 🧬 q-bio.TO

Testing randomness for cancer risk

classification 🧬 q-bio.TO
keywords cancercellriskdivisionsgivenhypothesestherecancerous
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There are numerous stochastic models for cancer risk for a given tissue. Many rely on the following two hypotheses. 1. There is a fixed probability that a given cell division will eventually lead to a cancerous cell. 2. Cell divisions are nefarious or not independently of each other. We show that recent data on cancer risk and number of stem divisions is consistent with hypotheses 1 and 2.

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