Which quartic polynomials have a hyperbolic antiderivative?

Every linear, quadratic or cubic polynomial having all real zeros is the derivative of a polynomial having all real zeros. The statement is false for higher degree polynomials. In particular, not every fourth degree polynomial with real zeros is the derivative of a polynomial having all real zeros. We derive a necessary and sufficient condition for a quartic polynomial to be the derivative of a polynomial having all real zeros. This condition is a single quadratic form inequality involving the zeros of the quartic polynomial.