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arxiv: 1406.7256 · v2 · pith:JCI42KRGnew · submitted 2014-06-27 · 🧬 q-bio.PE · math.AG

Identifiability of 3-Class Jukes-Cantor Mixtures

classification 🧬 q-bio.PE math.AG
keywords phylogeneticclassdifferentfindingidentifiabilityinvariantsjukes-cantornumber
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We prove identifiability of the tree parameters of the 3-class Jukes-Cantor mixture model. The proof uses ideas from algebraic statistics, in particular: finding phylogenetic invariants that separate the varieties associated to different triples of trees; computing dimensions of the resulting phylogenetic varieties; and using the disentangling number to reduce to trees with a small number of leaves. Symbolic computation also plays a key role in handling the many different cases and finding relevant phylogenetic invariants.

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