Painlev\'e VI and Hankel determinants for the generalized Jacobi Weight

We study the Hankel determinant of the generalized Jacobi weight $(x-t)^{\gamma}x^\alpha(1-x)^\beta$ for $x\in[0,1]$ with $\alpha, \beta>0$, $t < 0 $ and $\gamma\in\mathbb{R}$. Based on the ladder operators for the corresponding monic orthogonal polynomials $P_n(x)$, it is shown that the logarithmic derivative of Hankel determinant is characterized by a $\tau$-function for the Painlev\'e VI system.