Rigidity sensing explained by active matter theory
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🧬 q-bio.QM
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activematterrigiditytheoryadaptationanimalapproximatelycells
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The magnitude of traction forces exerted by living animal cells on their environment is a monotonically increasing and approximately sigmoidal function of the stiffness of the external medium. This observation is rationalized using active matter theory: adaptation to substrate rigidity results from an interplay between passive elasticity and active contractility.
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