pith. sign in

arxiv: 1303.2037 · v1 · pith:U3HPKRFAnew · submitted 2013-03-08 · 🧮 math.PR

Muller's ratchet clicks in finite time

classification 🧮 math.PR
keywords mutationspopulationratchettimeclicksdeleteriousfinitemuller
0
0 comments X
read the original abstract

We consider the accumulation of deleterious mutations in an asexual population, a phenomenon known as Muller's ratchet, using the continuous time model proposed in Etheridge et all. \cite{epw}. We show that for any parameter $\lambda>0$ (the rate at which mutations occur), for any $\alpha>0$ (the toxicity of the mutations) and for any size $N>0$ of the population, the ratchet clicks a.s. in finite time. That is to say the minimum number of deleterious mutations in the population goes to infinity a.s.

This paper has not been read by Pith yet.

discussion (0)

Sign in with ORCID, Apple, or X to comment. Anyone can read and Pith papers without signing in.